ISSUER PROFILE · CIK 0001636282
Spyre Therapeutics, Inc.SYRE
3 13D/G filings
2 distinct filers
18 insider transactions (365d)
Cross-Reference Snapshot
Distinct filers
2
multi-activist cluster
Insiders (365d)
18
0 buys · 15 sales
Latest short DTC
15.47
as of 2026-05-29
Institutional Consensus · 2025-12-31
Held by elite portfolio managers
1 holder · $21.70M
Point72 Asset Mgmt
13D/G Filings Timeline · 3 total
Form 4 Insider Transactions · last 365d
| Date | Insider | Role | Type | Shares | Price | Value |
|---|
| 2026-06-03 |
Sloan Sheldon |
officer |
Option exercise |
8,333 |
$27.46 |
$229K |
| 2026-06-03 |
Sloan Sheldon |
officer |
Sale |
8,333 |
$75.00 |
$625K |
| 2026-05-01 |
Burrows Scott L |
officer |
Option exercise |
12,500 |
$14.50 |
$181K |
| 2026-05-01 |
Sloan Sheldon |
officer |
Option exercise |
78,333 |
$27.46 |
$2.15M |
| 2026-05-01 |
Turtle Cameron |
director, officer |
Sale |
5,300 |
$69.54 |
$369K |
| 2026-05-01 |
Turtle Cameron |
director, officer |
Sale |
3,600 |
$70.77 |
$255K |
| 2026-05-01 |
Turtle Cameron |
director, officer |
Sale |
1,000 |
$71.76 |
$72K |
| 2026-05-01 |
Turtle Cameron |
director, officer |
Sale |
3,100 |
$73.14 |
$227K |
| 2026-05-01 |
Turtle Cameron |
director, officer |
Sale |
1,700 |
$74.23 |
$126K |
| 2026-05-01 |
Turtle Cameron |
director, officer |
Sale |
300 |
$74.96 |
$22K |
| 2026-05-01 |
Burrows Scott L |
officer |
Sale |
12,500 |
$71.37 |
$892K |
| 2026-05-01 |
Sloan Sheldon |
officer |
Sale |
21,306 |
$69.53 |
$1.48M |
| 2026-05-01 |
Sloan Sheldon |
officer |
Sale |
19,656 |
$70.61 |
$1.39M |
| 2026-05-01 |
Sloan Sheldon |
officer |
Sale |
8,777 |
$71.56 |
$628K |
| 2026-05-01 |
Sloan Sheldon |
officer |
Sale |
12,777 |
$72.94 |
$932K |
| 2026-05-01 |
Sloan Sheldon |
officer |
Sale |
10,358 |
$73.74 |
$764K |
| 2026-05-01 |
Sloan Sheldon |
officer |
Sale |
5,059 |
$74.60 |
$377K |
| 2026-05-01 |
Sloan Sheldon |
officer |
Sale |
400 |
$75.37 |
$30K |
FINRA Short Interest History
| Settlement | Short Interest | Days to Cover | % Δ vs prior |
|---|
| 2026-05-29 |
12,627,576 |
15.47 |
+1.7% |
| 2026-05-15 |
12,417,051 |
10.44 |
+1.6% |
| 2026-04-30 |
12,221,682 |
10.04 |
+4.7% |
| 2026-04-15 |
11,672,747 |
7.35 |
+11.8% |
| 2026-03-31 |
10,435,737 |
11.48 |
+4.4% |
| 2026-03-13 |
9,997,086 |
13.99 |
+0.1% |
| 2026-02-27 |
9,985,198 |
12.42 |
+1.2% |
| 2026-02-13 |
9,862,924 |
14.87 |
-1.2% |
| 2026-01-30 |
9,980,496 |
20.29 |
-0.9% |
| 2026-01-15 |
10,069,741 |
13.89 |
-13.5% |
| 2025-12-31 |
11,636,998 |
14.06 |
-1.5% |
| 2025-12-15 |
11,818,159 |
13.87 |
+5.9% |
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