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SCHEDULE Filed 2025-03-17 Event 2025-03-13 SEC 0001415889-25-008259 →

RA CAPITAL MANAGEMENT, L.P. → Mineralys Therapeutics, Inc. MLYS

Stake: 9.90% Shares: 6,287,597 CUSIP: 603170101 Class: Common Stock, par value $0.0001 per share
Composite Decision Signal · PASS (LOW BASE-RATE EDGE) Conviction Score: 29/100 · Filer 90d Win Rate: 0% · Hist. 90d Edge: +0.0%
  • Filer track record (20 filings): 0% 90d win rate, +0.0% 90d edge
  • High conviction ownership stake (9.9%)
  • Held by 1 tracked 13F institutional manager
  • 13 NPORT-P mutual funds holding CUSIP
  • Elevated short days-to-cover (5.3 DTC)

Item 4 — Purpose of Transaction

Not extracted from this filing — typically because it's an amendment (13D/A) and Item 4 is unchanged from the parent filing. Read the raw SEC filing →

Cross-References

Insider Activity (last 365d)
28 transactions
2 buys · 13 sales · 13 awards/exercises
Issuer Cluster
2 13D/G filings on this issuer
1 other filing besides this one
Filer Track Record
88 filings by this filer
87 other filings in the data moat
Short Interest · settle 2026-10-15
DTC 5.33
7,438,452 shares short · -4.7% vs prior

Institutional Consensus · 2025-12-31

Held by elite portfolio managers
1 holder · $43.81M
Point72 Asset Mgmt

Post-Filing Returns · since 2025-03-13 on MLYS

+1 day
0.0%
+5 days
0.0%
+30 days
0.0%
+60 days
0.0%
+90 days
0.0%
+180 days
0.0%

Anchor price 30.46 on closest trading day on/after 2025-03-13. Source: Yahoo Finance daily adj_close (split + dividend adjusted).

Form 4 Insider Transactions · last 365d

DateInsiderRoleTypeSharesPriceValue
2026-09-22 Slingsby Brian Taylor director Sale 104,320 $28.81 $3.01M
2026-08-10 Ferguson James J. III officer Award 102,400 — —
2026-08-10 Ferguson James J. III officer Award 135,000 $27.38 $3.70M
2026-08-10 Rodman David Malcom officer Option exercise 2,170 $16.00 $35K
2026-08-10 Rodman David Malcom officer Sale 2,170 $27.09 $59K
2026-07-15 Rodman David Malcom officer Sale 6,349 $26.61 $169K
2026-07-13 Congleton Jon director, officer Sale 10,700 $27.24 $291K
2026-07-13 Rodman David Malcom officer Option exercise 3,542 $10.20 $36K
2026-07-13 Rodman David Malcom officer Option exercise 4,167 $14.25 $59K
2026-07-13 Rodman David Malcom officer Option exercise 6,349 $1.08 $7K
2026-07-13 Rodman David Malcom officer Sale 14,058 $27.58 $388K
2026-07-09 Rodman David Malcom officer Option exercise 2,171 $16.00 $35K
2026-07-09 Rodman David Malcom officer Sale 2,171 $30.30 $66K
2026-06-17 Rodman David Malcom officer Option exercise 4,167 $14.25 $59K
2026-06-17 Rodman David Malcom officer Option exercise 417 $15.44 $6K
2026-06-17 Rodman David Malcom officer Sale 4,584 $25.00 $115K
2026-06-17 Karydas Daphne director Option exercise 3,000 $12.02 $36K
2026-06-17 Karydas Daphne director Sale 3,000 $25.00 $75K
2026-06-15 Rodman David Malcom officer Option exercise 3,542 $10.20 $36K
2026-06-15 Rodman David Malcom officer Sale 9,890 $23.81 $235K
2026-04-15 Rodman David Malcom officer Sale 6,348 $27.66 $176K
2026-04-13 Congleton Jon director, officer Sale 15,730 $26.83 $422K
2026-04-13 Rodman David Malcom officer Option exercise 6,349 $1.08 $7K
2026-04-13 Rodman David Malcom officer Option exercise 3,542 $10.20 $36K
2026-04-13 Rodman David Malcom officer Option exercise 4,167 $14.25 $59K
Showing 25 of 28

Other 13D/G Filings on Mineralys Therapeutics, Inc.

FiledFormFilerStakeShares
2025-03-17 SCHEDULE Samsara BioCapital, L.P. 9.10% 5,736,305 view →

Other Filings by RA CAPITAL MANAGEMENT, L.P.

FiledFormIssuerStakeShares
2026-10-26 SCHEDULE 13G Alector, Inc. — — view →
2026-10-22 SCHEDULE 13G Frazier Life Sciences Acquisition Corp. II — — view →
2026-09-22 SCHEDULE 13G BetterLife Pharma Inc. — — view →
2026-09-21 SCHEDULE 13D/A SIONNA THERAPEUTICS, INC. 14.30% 6,476,193 view →
2026-09-17 SCHEDULE 13D/A TYRA BIOSCIENCES, INC. — 14,130,492 view →
2026-09-03 SCHEDULE 13G JATT III Acquisition Corp — — view →
2026-08-17 SCHEDULE 13G Latigo Biotherapeutics, Inc. — — view →
2026-08-14 SCHEDULE 13D/A SEPTERNA, INC. — 5,525,324 view →
2026-08-11 SCHEDULE 13D/A Wave Life Sciences, Inc. — 34,314,406 view →
2026-08-10 SCHEDULE 13D/A SAB Biotherapeutics, Inc. — 9,609,852 view →
2026-07-23 SCHEDULE 13D/A ARTIVA BIOTHERAPEUTICS, INC. — 18,415,956 view →
2026-07-22 SCHEDULE 13D/A Freenome, Inc. — 15,367,270 view →
2026-07-21 SCHEDULE 13D/A VOR BIOPHARMA INC. — 12,937,855 view →
2026-07-20 SCHEDULE 13G Agenus Inc. — — view →
2026-07-07 SCHEDULE 13D/A Climb Bio, Inc. CLYM 33.00% 23,249,186 view →
2026-07-02 SCHEDULE 13D/A WEREWOLF THERAPEUTICS, INC. HOWL 4.10% 1,985,541 view →
2026-06-26 SCHEDULE 13D/A WEREWOLF THERAPEUTICS, INC. HOWL 6.00% 2,915,742 view →
2026-06-24 SCHEDULE 13D/A SOLID BIOSCIENCES INC. SLDB — 12,036,126 view →
2026-06-22 SCHEDULE 13D/A WEREWOLF THERAPEUTICS, INC. HOWL — 3,654,307 view →
2026-06-18 SCHEDULE 13D Parabilis Medicines, Inc. PBLS 23.80% 28,933,371 view →
Showing 20 of 87

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