SCHEDULE Filed 2025-04-03 Event 2025-03-31 SEC 0001104659-25-031764 →

Nantahala Capital Management, LLC → TALPHERA, INC. TLPH

Stake: 11.70% Shares: 1,992,519 CUSIP: 00444T209 Class: Common Stock, par value $0.001 per share

Composite Decision Signal · PASS (LOW BASE-RATE EDGE) Conviction Score: 21/100 · Filer 90d Win Rate: 0% · Hist. 90d Edge: +0.0%

Filer track record (3 filings): 0% 90d win rate, +0.0% 90d edge
High conviction ownership stake (11.7%)
Elevated short days-to-cover (6.3 DTC)
Short interest building (+47.7% vs prior settlement)

Item 4 — Purpose of Transaction

Not extracted from this filing — typically because it's an amendment (13D/A) and Item 4 is unchanged from the parent filing. Read the raw SEC filing →

Cross-References

Insider Activity (last 365d)

0 transactions

0 buys · 0 sales · 0 awards/exercises

Issuer Cluster

3 13D/G filings on this issuer

2 other filings besides this one

Filer Track Record

15 filings by this filer

14 other filings in the data moat

Short Interest · settle 2026-10-15

DTC 6.25

1,065,727 shares short · +47.7% vs prior

Post-Filing Returns · since 2025-03-31 on TLPH

+1 day

0.0%

+5 days

0.0%

+30 days

0.0%

+60 days

0.0%

+90 days

0.0%

+180 days

0.0%

Anchor price 1.19 on closest trading day on/after 2025-03-31. Source: Yahoo Finance daily adj_close (split + dividend adjusted).

Other 13D/G Filings on TALPHERA, INC.

Filed	Form	Filer	Stake	Shares
2025-04-02	SCHEDULE	Nantahala Capital Management, LLC	11.70%	1,992,519	view →
2018-02-14	SC	THREE ARCH PARTNERS IV LP	—	—	view →

Other Filings by Nantahala Capital Management, LLC

Filed	Form	Issuer	Stake	Shares
2026-10-07	SCHEDULE 13G	Research Alliance Corp III	—	—	view →
2026-08-14	SCHEDULE 13G	ADC Therapeutics SA	—	—	view →
2025-08-05	SCHEDULE	Xtant Medical Holdings, Inc. XTNT	49.10%	68,394,000	view →
2025-04-02	SCHEDULE	TALPHERA, INC. TLPH	11.70%	1,992,519	view →
2025-02-03	SCHEDULE	Evoke Pharma Inc	15.99%	254,639	view →
2024-10-01	SC	Evoke Pharma Inc	—	—	view →
2022-07-15	SC	IMAGEWARE SYSTEMS INC	—	—	view →
2022-01-06	SC	IMAGEWARE SYSTEMS INC	—	—	view →
2021-06-10	SC	IMAGEWARE SYSTEMS INC	—	—	view →
2021-04-12	SC	IMAGEWARE SYSTEMS INC	—	—	view →
2021-03-08	SC	IMAGEWARE SYSTEMS INC	—	—	view →
2020-11-19	SC	IMAGEWARE SYSTEMS INC	—	—	view →
2020-10-15	SC	IMAGEWARE SYSTEMS INC	—	—	view →
2019-06-17	SC	FTD Companies, Inc.	—	—	view →

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