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SC Filed 2018-02-07 Event — SEC 0000947871-18-000109 →

ORBIMED ADVISORS LLC → RHYTHM PHARMACEUTICALS, INC. RYTM

Stake: — Shares: —

Item 4 — Purpose of Transaction

Not extracted from this filing — typically because it's an amendment (13D/A) and Item 4 is unchanged from the parent filing. Read the raw SEC filing →

Cross-References

Insider Activity (last 365d)
80 transactions
17 buys · 36 sales · 22 awards/exercises
Issuer Cluster
5 13D/G filings on this issuer
4 other filings besides this one
Filer Track Record
145 filings by this filer
144 other filings in the data moat
Short Interest · settle 2026-09-30
DTC 14.14
10,767,698 shares short · +4.7% vs prior

Institutional Consensus · 2026-06-30

Held by elite portfolio managers
2 holders · $45.99M
Duquesne Family OfficePoint72 Asset Mgmt

Form 4 Insider Transactions · last 365d

DateInsiderRoleTypeSharesPriceValue
2026-09-14 Meeker David P director, officer Option exercise 50,000 $6.05 $303K
2026-09-14 Meeker David P director, officer Sale 6,439 $101.75 $655K
2026-09-14 Meeker David P director, officer Sale 30,746 $102.35 $3.15M
2026-09-14 Meeker David P director, officer Sale 8,698 $103.43 $900K
2026-09-14 Meeker David P director, officer Sale 1,817 $104.55 $190K
2026-09-14 Meeker David P director, officer Sale 2,300 $105.19 $242K
2026-08-13 Lee Jennifer Kayden officer Option exercise 35,000 $24.29 $850K
2026-08-13 Lee Jennifer Kayden officer Option exercise 21,601 $6.80 $147K
2026-08-13 Lee Jennifer Kayden officer Sale 75,834 $117.38 $8.90M
2026-08-12 Mazabraud Yann officer Option exercise 46,625 $6.80 $317K
2026-08-12 Mazabraud Yann officer Sale 2,300 $111.80 $257K
2026-08-12 Mazabraud Yann officer Sale 1,000 $112.86 $113K
2026-08-12 Mazabraud Yann officer Sale 3,605 $114.70 $413K
2026-08-12 Mazabraud Yann officer Sale 14,568 $115.43 $1.68M
2026-08-12 Mazabraud Yann officer Sale 18,208 $116.49 $2.12M
2026-08-12 Mazabraud Yann officer Sale 17,319 $117.47 $2.03M
2026-04-01 Mazabraud Yann officer Option exercise 12,875 — —
2026-04-01 Popovits Kimberly J director Award 6,808 — —
2026-04-01 Popovits Kimberly J director Award 10,257 $88.12 $904K
2026-04-01 Mazabraud Yann officer Option exercise 10,375 — —
2026-04-01 Mazabraud Yann officer Option exercise 2,500 — —
2026-03-12 Mathers Edward T director J 4,199 — —
2026-03-04 German Christopher Paul officer Option exercise 1,500 $17.97 $27K
2026-03-04 German Christopher Paul officer Sale 5,614 $89.56 $503K
2026-03-02 Mazabraud Yann officer Award 35,000 $94.94 $3.32M
Showing 25 of 80

Other 13D/G Filings on RHYTHM PHARMACEUTICALS, INC.

FiledFormFilerStakeShares
2026-10-13 SCHEDULE 13G JPMORGAN CHASE & CO — — view →
2020-06-26 SC MPM BIOVENTURES V, L.P. — — view →
2020-02-05 SC MPM BIOVENTURES V, L.P. — — view →
2019-02-12 SC MPM BIOVENTURES V, L.P. — — view →

Other Filings by ORBIMED ADVISORS LLC

FiledFormIssuerStakeShares
2026-10-08 SCHEDULE 13D/A ArriVent BioPharma, Inc. 5.80% 2,875,962 view →
2026-10-02 SCHEDULE 13D ADARx Pharmaceuticals, Inc. 14.00% 14,913,764 view →
2026-09-25 SCHEDULE 13D Electra Therapeutics, Inc. 11.00% 6,885,170 view →
2026-09-10 SCHEDULE 13D/A Braveheart Bio, Inc. 13.50% 12,175,159 view →
2026-08-18 SCHEDULE 13D BlossomHill Therapeutics, Inc. 8.90% 2,714,279 view →
2026-08-18 SCHEDULE 13D Braveheart Bio, Inc. 17.20% 12,175,159 view →
2026-08-10 SCHEDULE 13D/A MBX Biosciences, Inc. — 3,074,853 view →
2026-08-05 SCHEDULE 13D Yarrow Bioscience, Inc. 9.97% 266,306 view →
2026-07-29 SCHEDULE 13D Scribe Therapeutics, Inc. 7.20% 1,348,825 view →
2026-07-20 SCHEDULE 13D/A Q32 Bio Inc. — 4,127,987 view →
2026-06-24 SCHEDULE 13D/A Enliven Therapeutics, Inc. ELVN — 6,774,507 view →
2026-06-17 SCHEDULE 13D/A Enliven Therapeutics, Inc. ELVN 10.93% 7,634,630 view →
2026-06-15 SCHEDULE 13D/A Shattuck Labs, Inc. STTK — 9,021,127 view →
2026-06-01 SCHEDULE 13D/A Q32 Bio Inc. QTTB — 4,127,987 view →
2026-04-10 SCHEDULE 13D/A Adicet Bio, Inc. ACET 8.80% 844,787 view →
2026-01-27 SCHEDULE Corvus Pharmaceuticals, Inc. CRVS 10.30% 8,609,091 view →
2025-10-10 SCHEDULE Adicet Bio, Inc. ACET 9.60% 14,772,598 view →
2025-09-30 SCHEDULE MBX Biosciences, Inc. MBX 9.00% 4,002,887 view →
2025-07-21 SCHEDULE Passage BIO, Inc. PASG 7.82% 243,878 view →
2025-05-14 SCHEDULE Corvus Pharmaceuticals, Inc. CRVS 12.20% 9,785,423 view →
Showing 20 of 144

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