| Filed | Form | Filer | Stake | Shares | Intent | |
|---|---|---|---|---|---|---|
| 2019-07-23 | SC | Stonepine Capital Management, LLC | — | — | view → | |
| 2019-06-26 | SC | 5AM Ventures II LP | — | — | view → | |
| 2019-03-20 | SC | STONEPINE CAPITAL, L.P. | — | — | view → | |
| 2018-02-12 | SC | Stonepine Capital Management, LLC | — | — | view → |
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