| Filed | Form | Filer | Stake | Shares | Intent | |
|---|---|---|---|---|---|---|
| 2025-11-03 | SCHEDULE | RA CAPITAL MANAGEMENT, L.P. | — | — | view → | |
| 2025-03-03 | SCHEDULE | RA CAPITAL MANAGEMENT, L.P. | 13.70% | 20,013,733 | view → | |
| 2025-02-03 | SCHEDULE | RA CAPITAL MANAGEMENT, L.P. | 15.10% | 20,013,733 | view → | |
| 2023-08-11 | SC | RA CAPITAL MANAGEMENT, L.P. | — | — | view → | |
| 2022-10-21 | SC | RA CAPITAL MANAGEMENT, L.P. | — | — | view → | |
| 2022-07-06 | SC | RA CAPITAL MANAGEMENT, L.P. | — | — | view → | |
| 2022-07-05 | SC | ORBIMED ADVISORS LLC | — | — | view → | |
| 2022-02-07 | SC | Longitude Capital Partners III, LLC | — | — | view → | |
| 2021-06-04 | SC | RA CAPITAL MANAGEMENT, L.P. | — | — | view → | |
| 2020-11-25 | SC | Longitude Capital Partners III, LLC | — | — | view → | |
| 2020-09-23 | SC | ORBIMED ADVISORS LLC | — | — | view → | |
| 2020-09-21 | SC | RA CAPITAL MANAGEMENT, L.P. | — | — | view → | |
| 2020-07-20 | SC | Longitude Capital Partners III, LLC | — | — | view → | |
| 2020-07-10 | SC | RA CAPITAL MANAGEMENT, L.P. | — | — | view → |
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