Li Mingyu → Horizon Space Acquisition II Corp.

Item 4 of the Schedule 13D is amended and supplemented as follows: Consummation of the Business Combination On June 12, 2026, HSPT consummated the previously announced business combination pursuant to the Business Combination Agreement, dated as of May 9, 2025 ( the "Business Combination Agreement"), with SL Science Holding Limited, a Cayman Islands exempted company ("PubCo"), CW Mega Limited, a Cayman Islands exempted company and a wholly-owned subsidiary of PubCo ("Merger Sub I"), WW Century Limited, a Cayman Islands exempted company and a wholly-owned subsidiary of PubCo ("Merger Sub II"), and SL Bio Ltd., a Cayman Islands exempted company limited by shares ("SL Bio"). Pursuant to the Business Combination Agreement, (i) Merger Sub I merged with and into HSPT, with HSPT as the surviving entity and a wholly-owned subsidiary of PubCo (the "First Merger"), and (ii) following the First Merger, Merger Sub II merged with and into SL Bio, with SL Bio as the surviving entity and a wholly-owned subsidiary of PubCo (the "Second Merger," and together with the First Merger and the other transactions contemplated by the Business Combination Agreement, the "Business Combination"). Upon the consummation of the Business Combination, each of HSPT and SL Bio became a subsidiary of PubCo, and the shareholders of HSPT and SL Bio received ordinary shares of PubCo, par value $0.0001 per share ("PubCo Ordinary Shares"), as consideration and become shareholders of PubCo. Immediately prior to the First Merger Effective Time (as defined in the Business Combination Agreement), each HSPT Unit issued and outstanding was automatically detached, and the holder thereof was deemed to hold one (1) HSPT Ordinary Share and one (1) HSPT Right in accordance with the terms of the applicable unit (the "Unit Separation"). Each HSPT Right issued and outstanding was then automatically converted into one-tenth (1/10) of one HSPT Ordinary Share (the "Right Conversion"). Immediately following the Unit Separation and Right Conversion, each HSPT Ordinary Share (including those resulting from the Unit Separation and Right Conversion) issued and outstanding immediately prior to the First Merger Effective Time was automatically cancelled and ceased to exist in exchange for the right to receive one (1) newly issued PubCo Ordinary Share. Upon the consummation of the Business Combination on June 12, 2026, the Reporting Persons no longer beneficially owned any securities of HSPT, including any Ordinary Shares.