SCHEDULE Filed 2025-03-07 Event 2025-03-06 SEC 0000899140-25-000411 →

Sarissa Capital Management LP → Innoviva, Inc. INVA

Stake: 8.40% Shares: 5,237,161 CUSIP: 45781M101 Class: Common Stock, par value $0.01 per share

Composite Decision Signal · PASS (LOW BASE-RATE EDGE) Conviction Score: 33/100 · Filer 90d Win Rate: 0% · Hist. 90d Edge: +0.0%

Passive Schedule 13G filer baseline
High conviction ownership stake (8.4%)
Held by 1 tracked 13F institutional manager
19 NPORT-P mutual funds holding CUSIP
Elevated short days-to-cover (10.4 DTC)

Item 4 — Purpose of Transaction

Item 4 of the Schedule 13D is hereby amended by adding the following: The Reporting Persons may make additional sales of Common Stock or enter other transactions related to the Issuer's securities.

Cross-References

Insider Activity (last 365d)

0 transactions

0 buys · 0 sales · 0 awards/exercises

Issuer Cluster

7 13D/G filings on this issuer

6 other filings besides this one

Filer Track Record

28 filings by this filer

27 other filings in the data moat

Short Interest · settle 2026-10-15

DTC 10.36

7,265,728 shares short · +6.1% vs prior

Institutional Consensus · 2025-12-31

Held by elite portfolio managers

1 holder · $2.27M

Point72 Asset Mgmt

Post-Filing Returns · since 2025-03-06 on INVA

+1 day

0.0%

+5 days

0.0%

+30 days

0.0%

+60 days

0.0%

+90 days

0.0%

+180 days

0.0%

Anchor price 22.25 on closest trading day on/after 2025-03-06. Source: Yahoo Finance daily adj_close (split + dividend adjusted).

Other 13D/G Filings on Innoviva, Inc.

Filed	Form	Filer	Stake	Shares
2025-03-17	SCHEDULE	Sarissa Capital Management LP	4.70%	2,966,022	view →
2021-05-25	SC	Sarissa Capital Management LP	—	—	view →
2021-05-25	SC	GLAXOSMITHKLINE PLC	—	—	view →
2021-02-12	SC	GLAXOSMITHKLINE PLC	—	—	view →
2020-12-14	SC	Sarissa Capital Management LP	—	—	view →
2018-04-10	SC	GLAXOSMITHKLINE PLC	—	—	view →

Other Filings by Sarissa Capital Management LP

Filed	Form	Issuer	Stake	Shares
2026-08-27	SCHEDULE 13D/A	Amarin Corporation PLC/UK	6.09%	25,743,900	view →
2025-03-17	SCHEDULE	Innoviva, Inc. INVA	4.70%	2,966,022	view →
2023-09-05	SC	AMARIN CORP PLC\UK AMRN	—	—	view →
2023-06-21	SC	Alkermes plc. ALKS	—	—	view →
2023-06-12	SC	Alkermes plc. ALKS	—	—	view →
2023-06-12	SC	Sarissa Capital Management LP	—	—	view →
2023-02-28	SC	AMARIN CORP PLC\UK AMRN	—	—	view →
2023-02-27	SC	AMARIN CORP PLC\UK AMRN	—	—	view →
2023-02-21	SC	AMARIN CORP PLC\UK AMRN	—	—	view →
2023-01-11	SC	AMARIN CORP PLC\UK AMRN	—	—	view →
2022-10-11	SC	AMARIN CORP PLC\UK AMRN	—	—	view →
2022-07-06	SC	Alkermes plc. ALKS	—	—	view →
2022-01-10	SC	Alkermes plc. ALKS	—	—	view →
2021-11-19	SC	Alkermes plc. ALKS	—	—	view →
2021-09-10	SC	Alkermes plc. ALKS	—	—	view →
2021-05-27	SC	Alkermes plc. ALKS	—	—	view →
2021-05-25	SC	Innoviva, Inc. INVA	—	—	view →
2021-03-01	SC	IRONWOOD PHARMACEUTICALS INC IRWD	—	—	view →
2021-02-12	SC	Iterum Therapeutics plc ITRMF	—	—	view →
2020-12-14	SC	Innoviva, Inc. INVA	—	—	view →

Showing 20 of 27

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